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1

Clinical Laboratory Practice Recommendations for the Use of Cardiac Troponin in Acute Coronary Syndrome: Expert Opinion from the Academy of the American Association for Clinical Chemistry and the Task Force on Clinical Applications of Cardiac Bio-Markers of the International Federation of Clinical Chemistry and Laboratory Medicine

Wu, Alan H.B., Christenson, Robert H., Greene, Dina N., Jaffe, Allan S., Kavsak, Peter A., Ordonez-Llanos, Jordi, Apple, Fred S.

Journal:

Clinical Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 117 KB

english, 2018

2

Second and first trimester estimation of risk for Down syndrome: implementation and performance in the SAFER study

Andrew R. MacRae, Bernie N. Chodirker, Gregory A. Davies, Glenn E. Palomaki, George J. Knight, Jane Minett, Peter A. Kavsak, Ants Toi, David Chitayat, Paul G. Van Caeseele

Journal:

Prenatal Diagnosis

Année:

2010

Langue:

english

Fichier:

PDF, 100 KB

english, 2010

3

10.1038/23293

Thomsen, Gerald H., Zhu, Haitao, Kavsak, Peter, Abdollah, Shirin, Wrana, Jeffrey L.

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 298 KB

english, 1999

4

Autism spectrum disorder: When biochemical and genetic profiles don't match — Is sample size and selection bias the culprit?

Peter A. Kavsak

Journal:

Clinical Biochemistry

Année:

2011

Langue:

english

Fichier:

PDF, 116 KB

english, 2011

5

Assessment of a four hour delay for urine samples stored without preservatives at room temperature for urinalysis

Veljkovic, Kika, Rodríguez-Capote, Karina, Bhayana, Vipin, Pickersgill, Robin, Beattie, John, Clark, Lorna, Kavsak, Peter A.

Journal:

Clinical Biochemistry

Année:

2012

Langue:

english

Fichier:

PDF, 129 KB

english, 2012

6

Statistical issues with the determination of the troponin 99th percentile – Not just a problem for troponin?

Hickman, Peter E., Koerbin, Gus, Saenger, Amy K., Kavsak, Peter A.

Journal:

Clinical Biochemistry

Année:

2016

Langue:

english

Fichier:

PDF, 183 KB

english, 2016

7

Best Practices for Monitoring Cardiac Troponin in Detecting Myocardial Injury

Apple, Fred S., Jaffe, Allan S., Sharkey, Scott, Kavsak, Peter, Kontos, Michael C., Saenger, Amy K., Smith, Stephen

Journal:

Clinical Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 979 KB

english, 2017

8

Total Analytic Error for Low Cardiac Troponin Concentrations (≤10 ng/L) by Use of a High-Sensitivity Cardiac Troponin Assay

Kavsak, Peter A., Jaffe, Allan S., Greene, Dina N., Christenson, Robert H., Apple, Fred S., Wu, Alan H.B.

Journal:

Clinical Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 449 KB

english, 2017

9

Differences in total PSA results within and between manufacturers

Kittanakom, Saranya, Clark, Lorna, Roy, Chantele, Malinowski, Paul, Bamford, Karen, Lamers, Shana, Kavsak, Peter A.

Journal:

Clinical Biochemistry

Année:

2018

Langue:

english

Fichier:

PDF, 775 KB

english, 2018

10

The importance of tumour marker dual reporting during method transition: PSA high-dose hook effect detected

Kittanakom, Saranya, Donohue, Veronica, Beattie, Jacqueline, Clark, Lorna, Kavsak, Peter A.

Journal:

Clinical Biochemistry

Année:

2018

Langue:

english

Fichier:

PDF, 557 KB

english, 2018

11

Cardiac troponin and natriuretic peptide analytical interferences from hemolysis and biotin: educational aids from the IFCC Committee on Cardiac Biomarkers (IFCC C-CB)

Saenger, Amy K., Jaffe, Allan S., Body, Richard, Collinson, Paul O., Kavsak, Peter A., Lam, Carolyn S.P., Lefèvre, Guillaume, Omland, Tobjørn, Ordóñez-Llanos, Jordi, Pulkki, Kari, Apple, Fred S.

Journal:

Clinical Chemistry and Laboratory Medicine

Année:

2018

Langue:

english

Fichier:

PDF, 117 KB

english, 2018

12

Rapid atrophy of cardiac left ventricular mass in patients with non‐small cell carcinoma of the lung

Kazemi‐Bajestani, Seyyed Mohammad Reza, Becher, Harald, Butts, Charles, Basappa, Naveen S., Smylie, Michael, Joy, Anil Abraham, Sangha, Randeep, Gallivan, Andrea, Kavsak, Peter, Chu, Quincy, Baracos,

Journal:

Journal of Cachexia, Sarcopenia and Muscle

Année:

2019

Langue:

english

Fichier:

PDF, 586 KB

english, 2019

13

Educational Recommendations on Selected Analytical and Clinical Aspects of Natriuretic Peptides with a Focus on Heart Failure: A Report from the IFCC Committee on Clinical Applications of Cardiac Biomarkers

Kavsak, Peter A., Lam, Carolyn S.P., Saenger, Amy K., Jaffe, Allan S., Collinson, Paul, Pulkki, Kari, Omland, Tobjørn, Lefèvre, Guillaume, Body, Richard, Ordónñez-Llanos, Jordi, Apple, Fred S.

Journal:

Clinical Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 98 KB

english, 2019

14

Clinical evaluation of Ortho Clinical Diagnostics high-sensitivity cardiac Troponin I assay in patients with symptoms suggestive of acute coronary syndrome

Kavsak, Peter A., Mondoux, Shawn E., Sherbino, Jonathan, Ma, Jinhui, Clayton, Natasha, Hill, Stephen A., McQueen, Matthew, Mehta, Shamir R., Griffith, Lauren E., Devereaux, P.J., Worster, Andrew

Journal:

Clinical Biochemistry

Année:

2020

Fichier:

PDF, 396 KB

2020

15

Comparison of two biomarker only algorithms for early risk stratification in patients with suspected acute coronary syndrome

Kavsak, Peter A., Mondoux, Shawn E., Ma, Jinhui, Sherbino, Jonathan, Hill, Stephen A., Clayton, Natasha, Mehta, Shamir R., Griffith, Lauren E., McQueen, Matthew, Devereaux, P.J., Worster, Andrew

Journal:

International Journal of Cardiology

Année:

2020

Fichier:

PDF, 1.80 MB

2020

16

Lot-to-Lot Variation for Commercial High-Sensitivity Cardiac Troponin: Can We Realistically Report Down to the Assayâs Limit of Detection?

Wu, Alan H B, Kavsak, Peter A, Aakre, Kristin Moberg, Christenson, Robert H, Apple, Fred S, Peacock, W Frank, Hollander, Judd E, de Lemos, James A, Morrow, David, Januzzi, James, Jaffe, Allan S

Journal:

Clinical Chemistry

Année:

2020

Fichier:

PDF, 152 KB

2020

17

Challenges of implementing Point-of-Care Testing (POCT) glucose meters in a pediatric acute care setting

Peter A. Kavsak, Nuala Zielinski, Dailin Li, Patrick J. McNamara, Khosrow Adeli

Journal:

Clinical Biochemistry

Année:

2004

Langue:

english

Fichier:

PDF, 304 KB

english, 2004

18

Incomplete pediatric reference intervals for the management of patients with inborn errors of metabolism

Nathalie Lepage, Dailin Li, Peter A. Kavsak, Fiona Bamforth, John Callahan, Kent Dooley, Murray Potter

Journal:

Clinical Biochemistry

Année:

2006

Langue:

english

Fichier:

PDF, 105 KB

english, 2006

19

Vascular versus myocardial dysfunction in acute coronary syndrome: Are the adhesion molecules as powerful as NT-proBNP for long-term risk stratification?

Peter A. Kavsak, Dennis T. Ko, Alice M. Newman, Viliam Lustig, Glenn E. Palomaki, Andrew R. MacRae, Allan S. Jaffe

Journal:

Clinical Biochemistry

Année:

2008

Langue:

english

Fichier:

PDF, 303 KB

english, 2008

20

Cytokine elevations in acute coronary syndrome and ovarian cancer: A mechanism for the up-regulation of the acute phase proteins in these different disease etiologies

Peter A. Kavsak, Agnes Lee, Hal Hirte, Ed Young, Jack Gauldie

Journal:

Clinical Biochemistry

Année:

2008

Langue:

english

Fichier:

PDF, 128 KB

english, 2008

21

PAPP-A as a marker of increased long-term risk in patients with chest pain

Peter A. Kavsak, Xuesong Wang, Matthew Henderson, Dennis T. Ko, Andrew R. MacRae, Allan S. Jaffe

Journal:

Clinical Biochemistry

Année:

2009

Langue:

english

Fichier:

PDF, 475 KB

english, 2009

22

Biochip arrays for the discovery of a biomarker surrogate in a phase I/II study assessing a novel anti-metastasis agent

Peter A. Kavsak, Matthew Henderson, Patricia Moretto, Hal Hirte, Ken Evans, Donald Wong, Walter Korz, Sebastien J. Hotte

Journal:

Clinical Biochemistry

Année:

2009

Langue:

english

Fichier:

PDF, 363 KB

english, 2009

23

The use of a cytokine panel to define the long-term risk stratification of heart failure/death in patients presenting with chest pain to the emergency department

Peter A. Kavsak, Alice M. Newman, Dennis T. Ko, Andrew R. MacRae, Allan S. Jaffe

Journal:

Clinical Biochemistry

Année:

2010

Langue:

english

Fichier:

PDF, 148 KB

english, 2010

24

Identification of myocardial injury in the emergency setting

Peter A. Kavsak, Andrew Worster, John J. You, Mark Oremus, Adell Elsharif, Stephen A. Hill, P.J. Devereaux, Andrew R. MacRae, Allan S. Jaffe

Journal:

Clinical Biochemistry

Année:

2010

Langue:

english

Fichier:

PDF, 181 KB

english, 2010

25

High sensitivity cardiac troponin concentration cutoffs—is a healthy population the right reference population for those with underlying cardiac disease?

Peter A. Kavsak, Matthew J. McQueen

Journal:

Clinical Biochemistry

Année:

2010

Langue:

english

Fichier:

PDF, 114 KB

english, 2010

26

Early standardization of high sensitivity troponin T reporting - a lost opportunity

Peter A. Kavsak

Journal:

Clinical Biochemistry

Année:

2011

Langue:

english

Fichier:

PDF, 108 KB

english, 2011

27

High sensitivity troponin T concentrations in patients undergoing noncardiac surgery: A prospective cohort study

Peter A. Kavsak, Mike Walsh, Sadeesh Srinathan, Laurel Thorlacius, Giovanna Lurati Buse, Fernando Botto, Shirley Pettit, Matthew J. McQueen, Stephen A. Hill, Sabu Thomas, Marko Mrkobrada, Pablo Alonso

Journal:

Clinical Biochemistry

Année:

2011

Langue:

english

Fichier:

PDF, 256 KB

english, 2011

28

Elevated C-reactive protein in acute coronary syndrome presentation is an independent predictor of long-term mortality and heart failure

Peter A. Kavsak, Andrew R. MacRae, Alice M. Newman, Viliam Lustig, Glenn E. Palomaki, Dennis T. Ko, Jack V. Tu, Allan S. Jaffe

Journal:

Clinical Biochemistry

Année:

2007

Langue:

english

Fichier:

PDF, 334 KB

english, 2007

29

10.1038/35078562

Bonni, Shirin, Wang, Hong-Rui, Causing, Carrie G., Kavsak, Peter, Stroschein, Shannon L., Luo, Kunxin, Wrana, Jeffrey L.

Journal:

Nature Cell Biology

Année:

2001

Langue:

english

Fichier:

PDF, 450 KB

english, 2001

30

Risk Stratification in the Era of High-Sensitivity Troponin Assays

Andrew Worster, Peter A. Kavsak, Michael Brown

Journal:

Annals of Emergency Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 116 KB

english, 2012

31

The impact of the ESC/ACC redefinition of myocardial infarction and new sensitive troponin assays on the frequency of acute myocardial infarction

Peter A. Kavsak, Andrew R. MacRae, Viliam Lustig, Rakesh Bhargava, Rudy Vandersluis, Glenn E. Palomaki, Marie-Jeanne Yerna, Allan S. Jaffe

Journal:

American Heart Journal

Année:

2006

Langue:

english

Fichier:

PDF, 234 KB

english, 2006

32

Authors' response to Apple editorial

Peter A. Kavsak, Andrew R. MacRae, Alice M. Newman, Viliam Lustig, Glenn E. Palomaki, Dennis T. Ko, Jack V. Tu, Allan S. Jaffe

Journal:

Clinica Chimica Acta

Année:

2007

Langue:

english

Fichier:

PDF, 114 KB

english, 2007

33

Effects of contemporary troponin assay sensitivity on the utility of the early markers myoglobin and CKMB isoforms in evaluating patients with possible acute myocardial infarction

Peter A. Kavsak, Andrew R. MacRae, Alice M. Newman, Viliam Lustig, Glenn E. Palomaki, Dennis T. Ko, Jack V. Tu, Allan S. Jaffe

Journal:

Clinica Chimica Acta

Année:

2007

Langue:

english

Fichier:

PDF, 131 KB

english, 2007

34

“Upstream markers” provide for early identification of patients at high risk for myocardial necrosis and adverse outcomes

Peter A. Kavsak, Dennis T. Ko, Alice M. Newman, Glenn E. Palomaki, Viliam Lustig, Andrew R. MacRae, Allan S. Jaffe

Journal:

Clinica Chimica Acta

Année:

2008

Langue:

english

Fichier:

PDF, 193 KB

english, 2008

35

Another potential marker linking gender and cardiac mortality: PAPP-A — A new marker in risk stratification for women presenting with chest pain

Peter A. Kavsak, Matthew Henderson, Dennis T. Ko, Xuesong Wang, Andrew R. MacRae, Allan S. Jaffe

Journal:

Clinica Chimica Acta

Année:

2009

Langue:

english

Fichier:

PDF, 109 KB

english, 2009

36

Sensitive and high sensitivity cardiac troponin I concentrations in the Heart Outcomes Prevention Evaluation (HOPE) study — A high risk population

Peter A. Kavsak, Matthew J. McQueen

Journal:

Clinica Chimica Acta

Année:

2010

Langue:

english

Fichier:

PDF, 135 KB

english, 2010

37

Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT Domain

Abiodun A. Ogunjimi, Douglas J. Briant, Nadia Pece-Barbara, Christine Le Roy, Gianni M. Di Guglielmo, Peter Kavsak, Richele K. Rasmussen, Bruce T. Seet, Frank Sicheri, Jeffrey L. Wrana

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 881 KB

english, 2005

38

Cardiotoxicity associated with sunitinib

Peter A Kavsak, Sebastien Hotte

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 41 KB

english, 2008

39

Smad7 Binds to Smurf2 to Form an E3 Ubiquitin Ligase that Targets the TGFβ Receptor for Degradation

Peter Kavsak, Richele K. Rasmussen, Carrie G. Causing, Shirin Bonni, Haitao Zhu, Gerald H. Thomsen, Jeffrey L. Wrana

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 862 KB

english, 2000

40

Cardiac troponin testing in the acute care setting: Ordering, reporting, and high sensitivity assays—An update from the Canadian society of clinical chemists (CSCC)

Peter A. Kavsak, Lynn C. Allen, Fred S. Apple, Ronald A. Booth, Pak-Cheung Chan, Edgard Delvin, Albert Fraser, Lei Fu, Douglas Gornall, Christine Collier, Stephen Hill, Barry Hoffman, Yun Huang, Joël

Journal:

Clinical Biochemistry

Année:

2011

Langue:

english

Fichier:

PDF, 142 KB

english, 2011

41

The ABCs of clinical biochemistry

Peter A. Kavsak, Catherine Hammett-Stabler, Leslie Lai, Pierre Wallemacq, Robert H. Christenson

Journal:

Clinical Biochemistry

Année:

2012

Langue:

english

Fichier:

PDF, 97 KB

english, 2012

42

Whether it is personalized, precision, or mechanistic medicine - the clinical laboratory has a role

Peter A. Kavsak

Journal:

Clinical Biochemistry

Année:

2012

Langue:

english

Fichier:

PDF, 90 KB

english, 2012

43

Statistical and analytical approaches for assessing biomarkers: New approaches, new technologies, with the same-old rigor for evaluation

Matthew P.A. Henderson, Gregory R. Pond, Peter A. Kavsak

Journal:

Clinical Biochemistry

Année:

2012

Langue:

english

Fichier:

PDF, 101 KB

english, 2012

44

Peripheral Blood Monocyte Subset Assessment in Non–ST-Segment Elevation Myocardial Infarction Is Required

Peter A. Kavsak, Allan S. Jaffe

Journal:

Journal of the American College of Cardiology

Année:

2010

Langue:

english

Fichier:

PDF, 98 KB

english, 2010

45

Dichotomizing High-Sensitivity Cardiac Troponin T Results and Important Analytical Considerations

Peter A. Kavsak, Andrew Worster

Journal:

Journal of the American College of Cardiology

Année:

2012

Langue:

english

Fichier:

PDF, 90 KB

english, 2012

46

Analytical factors to consider when assessing a high-sensitivity cardiac troponin I assay compared to a contemporary assay in clinical studies

Rezvanpour, Atoosa, Shortt, Colleen, Clark, Lorna, Worster, Andrew, Kavsak, Peter A.

Journal:

Clinica Chimica Acta

Année:

2014

Langue:

english

Fichier:

PDF, 307 KB

english, 2014

47

Quality control material testing and the importance of “treating it like a patient's sample”

Kavsak, Peter A.

Journal:

Clinical Biochemistry

Année:

2014

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2014

48

Assessing the necessity of including a crossover period with dual reporting when changing total prostate-specific antigen methods

Rutledge, Angela C., Pond, Gregory R., Hotte, Sebastien J., Kavsak, Peter A.

Journal:

Clinical Biochemistry

Année:

2014

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2014

49

Predicting myocardial infarction and other serious cardiac outcomes using high-sensitivity cardiac troponin T in a high-risk stable population

McQueen, Matthew J., Kavsak, Peter A., Xu, Liqin, Shestakovska, Olga, Yusuf, Salim

Journal:

Clinical Biochemistry

Année:

2013

Langue:

english

Fichier:

PDF, 370 KB

english, 2013

50

Comparison of hs-cTnI, hs-cTnT, hFABP and GPBB for identifying early adverse cardiac events in patients presenting within six hours of chest pain-onset

Shortt, Colleen R., Worster, Andrew, Hill, Stephen A., Kavsak, Peter A.

Journal:

Clinica Chimica Acta

Année:

2013

Langue:

english

Fichier:

PDF, 213 KB

english, 2013